The device in question is a touchpad. I tried first with disabling it in BIOS, but then learned that in this particular laptop, this setting is actually there just to let Windows know that touchpad is not to be used, and not actually physically turning it off. So I tried various options: 1. To blacklist corresponding module, psmouse in this case. This doesn't work for me, as I'd like to use the trackpoint, that is handled by the same module. 2. To delete corresponding /dev/input/mouseX and /dev/input/eventX devices. That doesn't work, as device nodes get recreated upon reboot. 3. To disable touchpad using corresponding userspace daemons: gpm for console and synclient for X. This is what I use at the moment, but I'd prefer to have it disabled on "lower level". 4. To write a small program that would grab corresponding /dev/input/mouseX device, through passing EVIOCGRAB to ioctl, and then sleep forever. This program would be activated through an udev rule. Haven't actually tried this, I think it should do, but it's too much work. So I'm wondering, is there any other way to accomplish this?